YUMAB GmbH

YUMAB The success of next genera- tion antibody drug development relies on comprehensive discovery technolo- gies and strategies.

YUMAB bridges the gap between re- search innovation and novel therapies. Our advanced discovery platform provi- des access to challenging targets, enables new formats, and accelerates the deve- lopment of human antibodies at a high success rate.

From target discovery to fully characte- rised lead – our experienced team leads biotech and pharma teams worldwide through the development process as your trusted, de-risking partner.


Antibody Discovery

  • Advanced discovery platform for next generation biotherapeutics.
  • Access to challenging targets and new formats for drug discovery at high speed and success rate.
  • Fully integrated human antibody deve- lopment in one company – tailored to your needs.
  • Optimized discovery solution using antigen-positive cells as a target during selection.

Antibody Libraries

  • Universal human antibody libraries with more than 100 billion (1011) unique antibodies.
  • Highly productive pre-selected antibo- dy sequences.
  • Large epitope coverage and high hit rate.
  • Flexible business conditions.

Antibody Engineering

  • YUMAB® platform can be used for the engineering of externally generated already existing antibodies.
  • Two in-vitro evolution technologies.
  • Aktualisiert am

    26.07.2024
YUMAB GmbH 11. März 2025

VHH discovery for bispecifics – combination of in-vivo immunization and in-vitro display

Conventional IgG antibodies are powerful tools for many applications. Despite their flexibility, they also encounter limits of feasibility. With their size of 150 kDa they are limited in tissue penetration and less stable when it comes to harsh conditions, such as pH stress, temperature stress or protease rich environments, just to name a few.

Single domain antibodies (e.g. VHH) possess properties which circumvent these limitations. This case study demonstrates the power of YUMAB’s VHH discovery platform by combining in-vivo immunization and in-vitro display.

YUMAB GmbH 9. August 2024

YUMAB – pioneering antibody discovery since 2012

From target discovery to fully characterized lead – our experienced team leads biotech and pharma teams worldwide through the development process as your trusted, de-risking partner. Discover more in our corporate image video!